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Faculty and Staff
 
Name:
JI Kailong
Education:
Ph.D
Positions:
 
Academic title:
Associate Professor
Postal Code:
650223
Subject categories:
Botany
Mailing Address:
88 Xuefu Road, Kunming, 650223, Yunnan, China
E-mail:
jikailong@xtbg.ac.cn

Resume:
 

RESEARCH INTEREST
Natural Medicinal Chemistry (including bioactive natural products finding, structure modification, total synthesis)
Pharmacology (including anti-obesity, anti- acute liver injury, anti-ulcerative colitis, etc.)

EDUCATION AND TRAINING
2011.09-2016.06 M.S./Ph.D. in Plant Science, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Science
2007.09-2011.06 B.S. in Biology, Yunnan University, Kunming, China

WORK EXPERIENCE
2024.05-Present Associate Researcher, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Science, Kunming, China
2020.02-2024.04 Assistant Researcher, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Science, Kunming, China
2019.03-2020.01 Assistant Researcher, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China
2016.08-2019.02 Postdoctoral Scholar, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China

HONORS AND AWARDS
2016 Zhu Li Yue Hua Outstanding Doctoral Scholarship of Chinese Academy of Sciences

Direction:
 

Achievements:
 

Article:
 

(1) Kai-Long Ji, Yao-Yue Fan, Qi Gong, Qun-Fang Liu, Ming-Jun Cui, Kai-Cong Fu, Hai-Yan Zhang*, Jian-Min Yue*. Densely Functionalized Macrocyclic Sesquiterpene Pyridine Alkaloids from Maytenus austroyunnanensis. Journal of Natural Products, 2023, 86, 2315-2325. (First author) 

(2) Kai-Long Ji#, Wei, Liu#, Wei-Hang Yin#, Xiang-Rong Kong, Hong-Hong Xu, Zeng-Wei Lai*, Jing-Ya Li*, Jian-Min Yue*. A new class of potent liver injury protective compounds: structural elucidation, total synthesis and bioactivity study. Acta Pharmaceutica Sinica B, 2023, 13, 3414-3424. (Co-first author) 

(3) Kai-Long Ji#,*, Yan-Qing Tang#, Zheng-Yang Guo#, Pian-Chou Gongpan, Peng Sun, Jian-Mei Lu, Meng-Yuan Dai, Ting Li*. Natural geranylated sulphur-containing amides with inhibitory effect on Th17 differentiation. Chemistry & Biodiversity, 2023, 20, e202300373. (Co-first author/Co-corresponding author)  

(4) Kai-Long Ji#,*, Meng-Zhen Wu#, Chao-Ying Huang, Pian-Chou Gongpan, Peng Sun, Yi-Li Sun*, Jia Li, Chun-Fen Xiao, You-Kai Xu, Qing-Fei Fan, Hua-Bin Hu, Qi-Shi Song*. Alpinia hainanensis rhizome extract ameliorates dextran sulfate sodium-induced ulcerative colitis: active ingredient investigation and evaluation. Journal of Agricultural and Food Chemistry, 2022, 70, 3989-3999. (Co-first author/Co-corresponding author) 

(5) Kai-Long, Ji#, Wei, Liu#, Wei-Hang Yin, Jing-Ya Li*, Jian-Min Yue*. Quinoline alkaloids with anti-inflammatory activity from Zanthoxylum avicennae. Organic & Biomolecular Chemistry, 2022, 20, 4176-4182. (Co-first author)  

(6) Meng-Zhen Wu#, Pian-Chou Gongpan#, Meng-Yuan Dai, Peng Sun, Tian-Ping Huang, You-Kai Xu, Chun-Fen Xiao, Jia Li, Yi-Li Sun*, Kai-Long Ji*. Tetrahedron, 2022, 120, 132901. (Co-corresponding author) 

(7) Lan Zhou, Pian-Chou Gongpan, Qing-Fei Fan, Zhi Na, Feng-Mei Huang, Kai-Long Ji*, Qi-Shi Song*. Two new monoterpenoid indole alkaloids from Mappianthus iodoides stems. Natural Product Research, 2022, 36, 5235-5240. (Co-corresponding author) 

(8) Jin-Feng Li#, Kai-Long Ji#, Peng Sun, Qiang Cai, Xiao-Ling Zheng, Yi-Dian Xiao, Dong-Hua Cao, Chun-Fen Xiao, Zong-Yi Zhang, Xiao-Nian Li, Hua-Bin Hu, Zhi-Yong Yu*, You-Kai Xu*.  Structurally diverse steroids with nitric oxide inhibitory activities from Aglaia lawii leaves. Phytochemistry, 2021, 183, 112651. (Co-first author) 

(9) Kai-Long Ji, Yao-Yue Fan, Hio-Ha Kuok, Qun-Fang Liu, Ting Li, Jian-Min Yue*. Macrocyclic nonapeptides incorporating uncharacterized amino acids with inhibitory effects on Th17 differentiation. CCS Chemistry, 2021, 3, 175-189. (First author) 

(10) Kai-long Ji#,*, Meng-Yuan Dai#, Chun-Fen Xiao, You-Kai Xu*. Two new steroids with NO inhibitory effects from lansium domesticum. Natural Product Research, 2021, 35, 1147-1152. (Co-first author/Co-corresponding author)  

(11) Kai-Long Ji, Yao-Yue Fan, Zhan-Peng Ge, Li Sheng, You-Kai Xu, Li-She Gan, Jing-Ya Li, Jian-Min Yue*. Maximumins AD, rearranged labdane-type diterpenoids with four different carbon skeletons from Amomum maximum. Journal of Organic Chemistry, 2019, 84, 282-288. (First author) 

(12) Kai-long Ji#, Xiao-Qing Gan#, You-Kai Xu, Xiu-Fen Li, Juan Guo, Mahmoud M. Dahab, Ping Zhang*. Protective effect of the essential oil of Zanthoxylum myriacanthum var. pubescens against dextran sulfate sodium-induced intestinal inflammation in mice. Phytomedicine, 2016, 23, 883-90. (Co-first author) 

(13) Kai-long Ji, Xiao-Nian Li, Shang-Gao Liao, Hua-Bin Hu, Ren Li, You-Kai Xu*. Cytotoxic limonoids from the leaves of Walsura robusta. Phytochemistry Letters, 2016, 14, 234-238. (First author) 

(14) Kai-long Ji, Dong-Hua Cao, Xiu-Fen Li, Juan Guo, Ping Zhang*, You-Kai Xu*. Two new limonoids from the roots of Trichilia connaroides with inhibitory activity against nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells. Phytochemistry Letters, 2015, 14, 234-238. (First author) 

(15) Kai-long Ji, Ping Zhang, Xiao-Nian Li, Juan Guo, Hua-Bin Hu, Chun-Fen Xiao, Xiang-Qun Xie, You-Kai Xu*. Cytotoxic limonoids from Trichilia americana leaves. Phytochemistry, 2015, 118, 61-67. (First author) 

(16) Kai-long Ji, Ping Zhang, Hua-Bin Hu, Shuai Hua, Shang-Gao Liao*, You-Kai Xu*.  Limonoids from the leaves and twigs of Walsura yunnanensis. Journal of Natural Products, 2014, 77, 764-1769. (First author) 

(17) Kai-long Ji, Shang-Gao Liao, Xiao-Ling Zheng, Zhi Na, Hua-Bin Hu, Ping Zhang*, You-Kai Xu. Limonoids from the Fruits of Khaya ivorensis. Molecules, 2014, 19, 3004-3011. (First author) 

Community service:
 

Commitment to research the situation:
 

Yunnan Fundamental Research Projects- General Project, 202101AT070055, CNY 100,000, 2021-2024, Project leader 

Yunnan Fundamental Research Projects-Youth Project, 202101AU070148, CNY 50,000, (2021-2024), Project leader 

CAS Key Laboratory of Tropical Plant Resources and Sustainable Use for Youth Development Project, 20228012802, CNY 100,000, (2022-2024), Project leader 

NSFC General Project, 21772212, CNY 640,000, (2018-2021), Major participant 

NSFC Youth Project, 81602991, CNY 170,000, (2017-2019), Participant